I recently upgraded my system (which uses an nVidia graphics card) and found that Flash videos (e.g. YouTube) and PDF documents inverted some colours, so e.g. skin would appear blue!
To fix this for flash videos I enabled hardware acceleration in the Adobe configuration at /etc/adobe/mms.cfg:
EnableLinuxHWVideoDecode = 1
Note: Turns out that for me this results in Flash crashing periodically, so I’ve had to disable it and put up with the slightly disturbing experience of seeing everything as a window to Smurf village.
To fix this for PDFs I replaced epdfview with zathura. I’ve no idea why epdfview was showing a blue tint.